Marina Bio Lab


Getting Screened Early is Essential

If put off, you risk..

Late-stage diagnosis

You risk missing early signs, allowing the disease to progress.

Severe treatments

Late diagnosis often requires aggressive and invasive treatments with harsh side effects, drastically reducing your quality of life

Increased mortality

Skipping screening significantly raises your risk. Don't gamble with your life - get screened

So What Do We Do About It? Early Detection

By detecting the disease early, screening helps reduce colorectal cancer-related fatalities. Because so many people miss their screening appointments, the number of CRC diagnosis continues to rise. Due to the inconvenience of the currently accessible screening methods (such as stool samples and a colonoscopy), people typically postpone or ignore their screening.

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Stool-based Test

uses a stool sample; most people are uncomfortable with handling stool and mailing the sample. Very inconvenient. Not accurate (many false positives); ineffective for colon cancer screening.
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is the gold standard for screening, but there are challenges for some people – fear of invasive procedure, bowel preparation, and the high cost of the procedure to mention a few.

Protect Yourself in 3 Easy Steps

1: Order the kit

2) Have your sample collected

3) Receive your results

ColoScape™ Is A Simple Blood Test That Detects precancerous polyps or adenomas, allowing for early intervention and proper treatment

ColoScape™ Eliminates Screening Barriers!

> Safe and easy
> No need for fasting; no dietary restrictions before the test
> No bowel prep; no sedation
> Easy and convenient to your schedule
> Fast Turn-Around-Time (4-7 days from specimen receipt @ lab)

ColoScape™ Highly Sensitive And Highly Accurate Test For CRC

ColoscapeTM  Colorectal Cancer Test
Colorectal Cancer Mutation Detection  93%  93% to 100%
Precancerous Adenomas 62% 95.2%

How to screen for Colorectal Cancer

  • Since polyps and Colorectal Cancers bleed tiny amount of blood it can’t be seen in feces
  • The FDA has approved the Fecal immunochemical Test (FIT) tests to screen for Colorectal Cancer.
  • A FIT test uses antibodies to detect hidden blood in the stool.
  • Stool samples are collected by the patient using a kit and returned to the doctor. 
  • A positive finding with a FIT test is advised to be further evaluated by a physician.
Currently, FIT test is one of the most widely used CRC screening tests. FIT test uses stool or fecal sample and have the following shortfalls:

Are you at risk for colorectal cancer?

DiaCarta is now Offering ColoScape™ Test A simple blood test that detects 61 genetic mutations associated with colorectal cancer

Early Detection and Diagnosis Saves Lives

American Cancer Society recommends to start screening at age 45. Colorectal cancer is the second leading cause of cancer death in the US when women and men are combined. Colorectal cancer might be easier to treat when it’s small, hasn’t spread and detected early.

Highly Accurate,
Highly Sensitive

  • Blood Test
  • Convenient
  • No fasting needed
  • No bowel preparation
  • No dietary restrictions
ColoScape TM Test Sensitivity Specificity
Colorectal Cancer Mutation Detection 93% 100%
Precancerous Adenomas 62% 95.2%

Note: ColoScape™ has been validated as a Lab Developed Test compliant with CLIA regulations. This test is not a replacement for a colonoscopy. This is intended as a complementary test to the recommended screening method(s). Patients with “Positive” results are advised to seek the guidance of a healthcare provider for further evaluation. Patients with “Negative” results should continue to follow the recommended guidelines for colorectal screening.

  • Sensitivity to precancerous lesions is poor at around 22%. 
  • Positive test of blood in your stool alone cannot diagnose cancer.
  • 20% to 30% of FIT positive patients are found to have negative colonoscopy, are burdened with high unnecessary procedure costs *(Endosc Int Open. 2018 Sep; 6(9): E1140–E1148.
  • Half of all patients referred for colonoscopy fail to complete the procedure, because of non-compliance due to inconvenience or other factors. 
  • Patient-reported barriers to screening completion include lack of perceived risk for CRC, fear of pain, and concerns about bowel preparation, lack of insurance coverage etc.
  • Colorectal Cancer is the third most common cancer in the U.S
  • It is the 2nd leading cause of cancer related deaths
  • American Cancer Society (ACS) recommends that adults aged 45–75 years undergo screening.
  • 20% higher incidence in black persons rather than white, with fatality rate 40% higher in blacks
  • Most Colorectal Cancers (CRC) begin as a growth, or lesion, in the tissue that lines the inner surface of the colon or rectum. 
  • Lesions may appear as raised polyps, (a growth that protrudes from a mucous membrane) that may be attached to the inner surface of the colon or rectum with or without a stalk.
  • Colorectal polyps are common in people older than 50 years of age, and most do not become cancer. However, a certain type of polyp known as an adenoma (tumor) most likely to become a cancer.
  • Most CRCs develop from adenomas, among which “advanced” adenomas are considered to be the clinically relevant precursors of CRC. 

How accurate is a FIT test?

  • A positive FIT test does not mean that a person has Colorectal Cancer, a healthcare professional will advise the next steps.
  • Pre-cancerous polyp or cancer can be missed if the polyps wasn’t bleeding when test was done.
  • Sensitivity to Advanced Adenomas is about 40%,  Am J Gastroenterol. 2020 Jan; 115(1): 56–69.
  • Colorectal Cancer after negative colonoscopy in fecal immunochemical test-positive participants from a colorectal cancer screening program – PubMed
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